Aztofa Ointment is a prescription topical medication containing Tofacitinib, a Janus kinase (JAK) inhibitor. It works by reducing immune system overactivity and inflammation, making it useful for inflammatory skin conditions such as atopic dermatitis and psoriasis. By targeting specific pathways that cause redness, itching, and scaling, Aztofa provides relief where standard topical steroids or immunomodulators may not be effective.